EFFECTS OF SENA TORA LEAVE EXTRACT ON CARBON TETRACHLORIDE INDUCED TOXICITY.

EFFECTS OF SENA
TORA
LEAVE EXTRACT ON CARBON TETRACHLORIDE INDUCED TOXICITY.
CHAPTER ONE
1.0     INTRODUCTION
       Many of the developing countries
including African countries like Nigeria practice traditional medicine as its
main source of health care. This traditional medicine is normally gotten from
plant origin [Rehan Ahmad et al, 2008,
Stephen bent, 2008].Today nearly 88 percent of the global populations switch to
plant derived medicines as their first line of defence for maintaining health
and combating diseases [Kintzois et al,2006].
Presently there are about 60 types of medicinal plants that have been
recognised in primary health care and are classified according to their
pharmacological actions such as peptic ulcers, anti flatulence, laxative, anti
diarrhoea and anti hepatic[Viomolos et al,2003].
However in future the discovery of novel therapeutic agents will be only
dependent on plant origin [Perulmalsamy et
al
, 1999].
        Senna tora is an example of traditional medicine with
pharmacological actions as anticholesterolemic,antispasmodic,carninitative, emolliants,
ophthalmic and purgative [Polunin and Stanton,1984,Yeung,1985,Manandhar, 2002].
It can be cardiotonic, antiperiodic, anthelminitic and expectorant  and can also be used in treating  cogh,leprosy ,ring worm
,colic,flatulence,constipation and other disorders[Nature serve,2007]. Senna tora formally regarded as cassia
tora is capable of suppressing  the
production of prostaglandins and other inflammatory agonists such as cytokines,
histamine, kinin and free radical.manila,1998 buttressed his observations
confirming its use in the treatment of constipation, edema and liver protection
in Korea.

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